Overview

Map the scientific landscape of human aging through a Popperian lens: sharp claims, risky predictions, severe tests, rival explanations, and traceable primary sources.

We focus on:

• Explaining major theories of aging for laypeople and practitioners.
• Making predictions explicit and separating core claims from auxiliary assumptions.
• Tracking evidence and disconfirmations with citations to primary sources.
• Proposing simple, cheap, fast experiments — often in mice — that can decisively discriminate between rivals.

Explore the theories below and browse proposed experiments. A lightweight comparison rubric is being piloted; scoring and weights will evolve as evidence accumulates. Contribute improvements as we refine the map.

Theories of Aging

Start with these:

• Epigenetic Information (Sinclair)
• Bioelectric / Morphogenetic Control (Levin)
• SENS Damage Repair (de Grey)
• Resilience / Criticality (Fedichev)
• Pathogen Control (Lidsky)
• Programmatic Epigenetic Aging (de Magalhães)
• Longevity Bottleneck (Various Proponents)
• Classic Models (Medawar, Williams, Hamilton, Kirkwood)
• Other Theories